Welcome to EcoProDB

E. coli protein database (EcoProDB) integrates protein information identified on 2-D gels along with other resources to provide the comparative platform for the expression levels of many heterogeneous proteins under different genetic and environmental conditions using the interactive interface and search mechanism.

EcoProDB services integrated protein information, localization, theoretical 2-D map and experimental 2-D map.

 Comparable subcellular localization

For the comparative subcelluar proteomics, the proteins in EcoProDB were assigned into cytosol, periplasm, inner or outer membrane by integrating them from various databases and the published literature.
The Comparable subcellular localization shows a browsable list of proteins with the subcellular location annotated in UniProt, published literature and ECCE database.

 Theoretical 2-D map

Theoretical 2-D map plots a map of the theoretical isoelectric point (pI) versus the theoretical molecular mass (Mw) of the open reading frames of all data set. These values are calculated using Compute pI/Mw tool.
Each spot of the map is linked to the detailed information including function, expression, literature, experimental 2-D data and cross-references

 Experimental 2-D map

Experimental 2-D map provides a collection of all the 2-DE gels or their autoradiogram of E. coli which have been published last three decades. Proteins were collected with their IDs with their properties including protein name, accession number, functional category, sequence coverage, abundance, fold change, identification method and clarifying different experimental conditions. Using this information, history of the research on a specific protein can be easily recognized in a sight.

What's new?

(November 16, 2006) Updated the EcoProDB server and added 2DPAGE Map release 0, beta version.

EcoProDB open

(June 18, 2006) Installed the EcoProDB E. coli protein database server, release 0, beta version.


This database was made possible by incorporating numerous data generated by researchers worldwide.
We, the EcoProDB team, would like to thank all the contributors.
This DB was made possible by the Korea Systems Biology Program of the Ministry of Science and Technology.


The 2-D gel pictures and autoradiograms in the EcoProDB are copyright protected by the corresponding publishers. We thank the publishers who gave us permission to show them in the EcoProDB.

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Bioinformatics Research Center Metabolic & Biomolecular Engineerging Lab. Korea Advanced Institute of Science & Technology